Meet The Chef: Jhomeny Ramos

Award-winning Chef Jhomeny Ramos brings the flavors of Jalisco, Mexico, to Main Street in Mesa.

With family roots in Guadalajara, Ramos grew up connected to the ingredients, recipes and traditions that now shape his cooking at Guadalupe on Main. His approach is personal, grounded in family history and focused on making Mexican food feel welcoming to everyone at the table.

Ramos’ work has earned recognition, including Phoenix Magazine’s 2026 Best Chef and Best Mole at the 2025 Sunday Dinner at The Duce competition.

From Guadalajara to Mesa

Ramos found inspiration in the kitchen early, learning from the flavors of Jalisco and building his own style around them. Guadalupe on Main carries that family connection forward. The restaurant is named for his grandmother, and Ramos continues to draw from the food traditions that shaped him.

“I want people to know that when they come try Mexican food, that it's coming from my kitchen,” Ramos says.

The Mole Worth Knowing About

If there’s one dish Ramos wants you to try, it’s the mole. “It's one of the things that almost every ticket that's rung in, someone's ordering the mole.”

His recipe builds flavor with ingredients including chiles, achiote and piloncillo. Ramos also keeps accessibility in mind as he cooks. “I still like to keep things, you know, gluten-free, dairy-free, because I don't like customers feeling like they're left out."

That attention has earned his mole recognition beyond the restaurant, including a Best Mole award in 2025. It also reflects Ramos’ larger approach: start with the flavors of Jalisco, stay connected to family and make room for more people to enjoy the experience.

A Mesa Restaurant With a Family Story

Beyond the mole, Guadalupe on Main gives visitors another way to experience Mesa through local flavor. Ramos’ award-winning cooking connects Guadalajara to Main Street through recipes that feel deeply personal. It’s the kind of place that rewards travelers willing to look a little closer at Mesa’s food scene and find the stories behind the plate.

You haven't tasted Mesa, until you've tried Guadalupe on Main

FAQs

Who is Chef Jhomeny Ramos?
Jhomeny Ramos is the award-winning chef behind Guadalupe on Main in Mesa, Arizona. His cooking is inspired by his family roots in Guadalajara and the culinary traditions of Jalisco, Mexico.
What awards has Chef Jhomeny Ramos won?
Ramos won Best Mole at the 2025 Sunday Dinner at The Duce competition and was named Phoenix Magazine’s 2026 Best Chef.
What is Chef Jhomeny Ramos known for?
Ramos is especially known for his mole, one of the most frequently ordered dishes at Guadalupe on Main.
What ingredients are in Jhomeny Ramos’ mole?
Ramos says his mole incorporates ingredients including chiles, achiote and piloncillo.
Does Guadalupe on Main offer gluten-free or dairy-free options?
Ramos says he intentionally works to keep dishes gluten-free and dairy-free when possible because he doesn’t want guests to feel left out.
What kind of food does Guadalupe on Main serve?
Guadalupe on Main serves Mexican food inspired by Jalisco, with Ramos’ family roots and personal cooking style at the center of the menu.

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